alternatives to aromatase inhibitors

in this review, we discussed some significant natural chemical compounds with their mechanisms of actions, which can be very effective against the breast cancer and can be more potent by their proper modifications and further clinical research. the etiology of breast cancer and proliferation of cancerous cells is generally mediated by a number of mechanisms or pathways [13–16]. the development of targeted therapy in tnbc is very challenging, though lehmann et al. from many studies, it is evidenced that many …

tamoxifen alternatives premenopausal

these studies add to the large body of existing data related to adjuvant endocrine therapy in premenopausal women with breast cancer and provide additional therapeutic options in those at high risk of disease recurrence. as is described in detail below, the determination of which premenopausal women should receive endocrine therapy in combination with os/oa is complex because of issues related to both efficacy and tolerability (see below, section contemporary trials of ovarian suppression). in contrast to these data, subgroup analyses …

tamoxifen alternatives 2021

for the full follow-up period (median = 11.6 years), 103 recurrences were reported in the anastrozole arm and 118 in the tamoxifen arm. she and her co-investigators wanted to compare these two treatments at an earlier stage of breast cancer, dcis, which was once called stage 0. the study dr. sestak presented updated the blinded efficacy of anastrozole vs tamoxifen in preventing breast cancer recurrences, with an emphasis on the posttreatment phase. there were 9 her2-negative recurrences in the anastrozole …

alternatives to arimidex and tamoxifen

blocking hormone receptors or decreasing the amount of estrogen produced in the body is the standard way to treat hormone receptor-positive breast cancer. these treatment options may be preferred because they are effective and tend to carry a lower risk of severe side effects associated with tamoxifen. on the other hand, tamoxifen is an option to prevent breast cancer in premenopausal women. serious side effects may include an increased risk of uterine or endometrial cancer and blood clots in the …